Harakawa K, Kawarai S, Kryukov K, Nakagawa S, Moriya S,Imakawa K.
Buccal Swab Samples from Japanese Brown Cattle Fed with Limonite Reveal
Altered Rumen Microbiome.
Animals (Basel). 2024 Jul 3;14(13):1968. doi:10.3390/ani14131968.
Bhattacharjee J, Rolfo A, Barbosa BF,Imakawa K, Ermini L.
Editorial: Developmental biology and endocrine research for a successful pregnancy.
Front Endocrinol (Lausanne). 2024 May 13;15:1411864. doi: 10.3389/fendo.2024.1411864.
Sakurai T, Kusama K, Imakawa K.
Progressive Exaptation of Endogenous Retroviruses in Placental Evolution in Cattle.
Biomolecules. 2023 Nov 21;13(12):1680. doi: 10.3390/biom13121680.
Inenaga T, Fukuoka K, Sumida M, Aiba S, Nishikaku K, Matsuno Y, Kobayashi
T, Imakawa K.
Low proviral load in the Kumamoto strain of Japanese Brown cattle infected with the bovine leukemia virus.
BMC Vet Res. 2023 Oct 2;19(1):185. doi: 10.1186/s12917-023-03738-6.
Nakamura K, Kusama K, Hori M, Imakawa K.
Global analyses and potential effects of extracellular vesicles on the establishment of conceptus implantation during the peri-implantation period.
J Reprod Dev. 2023 Jul 25. doi: 10.1262/jrd.2023-044.
Bai R, Kusama K, Matsuno Y, Bai H, Sakurai T, Kimura K, Imakawa K.
Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period.
Front Endocrinol (Lausanne). 2023 Feb 21;14:1075030. doi: 10.3389/fendo.2023.1075030. eCollection 2023.
Hossain MB, Kobayashi T, Makimoto S, Matsuo M, Nishikaku K, Tan BJY, Rahman A, Rajib SA, Sugata K, Ohnuki N, Saito M, Inenaga T, Imakawa K, Satou Y.
Clone Dynamics and Its Application for the Diagnosis of Enzootic Bovine Leukosis.
J Virol. 2022 Dec 19:e0154222. doi: 10.1128/jvi.01542-22.
Sharawy HA, Hegab AO, Risha EF, El-Adl M, Soliman WT, Gohar MA, Fahmy RA, Farag VM, Imakawa K, Bazer FW, James D, Zaghloul A, Abdalla AA, Rabie MM, Elmetwally MA.
The vaginal and uterine blood flow changes during the ovsynch program and its impact on the pregnancy rates in Holstein dairy cows.
BMC Vet Res. 2022 Sep 17;18(1):350. doi: 10.1186/s12917-022-03444-9.
Imakawa K, Kusama K, Kaneko-Ishino T, Nakagawa S, Kitao K, Miyazawa T, Ishino F.
Endogenous Retroviruses and Placental Evolution, Development, and Diversity.
Cells. 2022 Aug 8;11(15):2458. doi: 10.3390/cells11152458.
Imakawa K, Matsuno Y, Fujiwara H.
New Roles for EVs, miRNA and lncRNA in Bovine Embryo Implantation.
Front Vet Sci. 2022 Jul 15;9:944370. doi: 10.3389/fvets.2022.944370.
Bai H, Kawahara M, Takahashi M, Imakawa K.
Recent progress of interferon-tau research and potential direction beyond pregnancy recognition.
J Reprod Dev. 2022 Jul 23. doi: 10.1262/jrd.2022-061.
Nishikaku K, Yonezawa T, Nishibori M, Harada M, Kawaguchi F, Sasazaki S,
Torii Y, Imakawa K, Kawai K, Liu J, Mannen H, Kobayashi T.
Phylogenomics and Spatiotemporal Dynamics of Bovine Leukemia Virus Focusing on Asian Native Cattle: Insights Into the Early Origin and Global Dissemination.
Front Microbiol. 2022 Jun 24;13:917324. doi: 10.3389/fmicb.2022.917324.
Rashid MB, Marey MA, Fukuda K, Haneda S, Kusama K, Shimada M, Imakawa K, Miyamoto A.
Intrauterine infusion of low levels of interferon-tau on day-8 post-estrus stimulates the bovine endometrium to secrete apolipoprotein-A1: A possible implication for early embryo tolerance.
Am J Reprod Immunol. 2022 Jul 4:e13592. doi: 10.1111/aji.13592.
Oghbaei F, Zarezadeh R, Jafari-Gharabaghlou D, Ranjbar M, Nouri M, Fattahi A,Imakawa K.
Epithelial-mesenchymal transition process during embryo implantation.
Cell Tissue Res. 2022 Apr;388(1):1-17. doi: 10.1007/s00441-021-03574-w.
Yamada A, Ohtsuki K, Shiga N, Green JA, Matsuno Y, Imakawa K.
Epithelial-mesenchymal transition and bi- and multi-nucleated trophoblast cell formation in ovine conceptuses during the peri-implantation period.
J Reprod Dev. 2022 Apr1;68(2):110-117. doi: 10.1262/jrd.2021-088.
Matsuno Y, Kusama K, Imakawa K.
Characterization of lncRNA functioning in ovine conceptuses and endometria
during the peri-implantation period.
Biochem Biophys Res Commun. 2022 Feb 26;594:22-30. doi: 10.1016/j.bbrc.2022.01.064.
Kusama K, Bai R, Matsuno Y, Ideta A, Sakurai T, Nagaoka K, Hori M, Imakawa K.
Characterization of Serum Metabolome and Proteome Profiles Identifies SNX5 Specific for Pregnancy Failure in Holstein Heifers.
Life (Basel). 2022 Feb18;12(2):309. doi: 10.3390/life12020309.
Nakamura K, Kusama K, Hori M, Imakawa K.
The effect of bta-miR-26b in intrauterine extracellular vesicles on maternal immune system during the implantation period.
Biochem Biophys Res Commun. 2021 Oct 8;573:100-106. doi:10.1016/j.bbrc.2021.08.019.
Kusama K, Rashid MB, Kowsar R, Marey MA, Talukder AK, Nagaoka K, Shimada
M,Khatib H, Imakawa K, Miyamoto A.
Day 7 Embryos Change the Proteomics and Exosomal Micro-RNAs Content of Bovine Uterine Fluid: Involvement of Innate Immune Functions.
Front Genet. 2021 Jun 28;12:676791. doi:10.3389/fgene.2021.676791.
Fiorenza MF, Marey MA, Rashid MB, Zinnah MA, Ma D, Morillo VA, Kusama K,Shimada
M, Imakawa K, Antoniazzi AQ, Miyamoto A.
Neutrophils recognize and amplify IFNT signals derived from day 7 bovine embryo for stimulation of ISGs expression in vitro: A possible implication for the early maternal recognition of pregnancy.
Biochem Biophys Res Commun. 2021 May 14;553:37-43. doi:10.1016/j.bbrc.2021.03.037.
Formation of fibrin at sights of conceptus adhesion in the ewe
Matsuno Y, Amin YA, Kusama K, Imakawa K.
Reproduction. 2021 May 10;161(6):709-720. doi: 10.1530/REP-20-0531.
PMID: 33852426
A target enrichment high throughput sequencing system for characterization of BLV whole genome sequence, integration sites, clonality and host SNP
Ohnuki N, Kobayashi T, Matsuo M, Nishikaku K, Kusama K, Torii Y, Inagaki
Y, Hori M, Imakawa K, Satou Y.
Sci Rep. 2021 Feb 25;11(1):4521. doi: 10.1038/s41598-021-83909-3.
PMID: 33633166
反芻動物の着床期における細胞外分泌小胞エクソソームの役割と展望
Emerging Role of Extracellular Vesicles in Embryo-Maternal Communication throughout Implantation Processes.
Nakamura K, Kusama K, Suda Y, Fujiwara H, Hori M, Imakawa K.
Int J Mol Sci. 2020 Aug 1;21(15):5523. doi: 10.3390/ijms21155523.
PMID: 32752293
胎盤の進化や多様性に関与するレトロトランスポゾン
Retrotransposons on the development and diversity of placenta
Otsuki K, Nakagawa S, Imakawa K.
J. Mamm. Ova Res.Vol.37(2),95-106,2020
Genetic variation in Japanese Holstein cattle for EBL development.
Inagaki Y, Kobayashi T, Suda Y, Kusama K, Imakawa K.
BMC Vet Res. 2020 Oct 28;16(1):407. doi: 10.1186/s12917-020-02625-8.
PMID:33115449
Bai R, Latifi Z, Kusama K, Nakamura K, Shimada M, Imakawa K.
Induction of immune-related gene expression by seminal exosomes in the
porcine endometrium.
Biochem Biophys Res Commun. 2017 in press
PMID: 29155178
外国人留学生で来ていたZeinab Latifiさんの研究成果が掲載されました。
Latifi Z, Fattahi A, Ranjbaran A, Nejabati HR, Imakawa K. Potential roles of metalloproteinases of endometrium-derived exosomes
in embryo-maternal crosstalk during implantation. 2017. J Cell Physiol.
in press PMID: 29115666
今川教授が発見した反芻動物の妊娠認識物質インターフェロンタウ(Imakawa et al., Nature 1987)の発見30周年を記念した特集に
Ezashi T, Imakawa K. Transcriptional control of IFNT expression. Reproduction. 2017 154:F21-F31. PMID: 28982936
で投稿されました。
Sakurai T, Nakagawa S, Bai H, Bai R, Kusama K, Ideta A, Aoyagi Y, Kaneko K, Iga K, Yasuda J, Miyazawa T, Imakawa K. Novel endogenous retrovirus-derived transcript expressed in the bovine
placenta is regulated by WNT signaling. Biochem J. 2017 474:3499-3512.
PMID: 28899944
Kusama K, Nakamura K, Bai R, Nagaoka K, Sakurai T, Imakawa K.
Intrauterine exosomes are required for bovine conceptus implantation.
Biochem Biophys Res Commun. 2017 in press
PMID: 29196267
Bai R, Latifi Z, Kusama K, Nakamura K, Shimada M, Imakawa K.
Induction of immune-related gene expression by seminal exosomes in the
porcine endometrium.
Biochem Biophys Res Commun. 2017 in press
PMID: 29155178
外国人留学生で来ていたZeinab Latifiさんの研究成果が掲載されました。
Latifi Z, Fattahi A, Ranjbaran A, Nejabati HR, Imakawa K. Potential roles of metalloproteinases of endometrium-derived exosomes
in embryo-maternal crosstalk during implantation. 2017. J Cell Physiol.
in press PMID: 29115666
今川教授が発見した反芻動物の妊娠認識物質インターフェロンタウ(Imakawa et al., Nature 1987)の発見30周年を記念した特集に
Ezashi T, Imakawa K. Transcriptional control of IFNT expression. Reproduction. 2017 154:F21-F31. PMID: 28982936
で投稿されました。
Sakurai T, Nakagawa S, Bai H, Bai R, Kusama K, Ideta A, Aoyagi Y, Kaneko K, Iga K, Yasuda J, Miyazawa T, Imakawa K. Novel endogenous retrovirus-derived transcript expressed in the bovine
placenta is regulated by WNT signaling. Biochem J. 2017 474:3499-3512.
PMID: 28899944
Matsumoto K, Imakawa K, Hayashi C. Successful pregnancy and live birth from a hypogonadotropic
hypogonadism woman with low serum estradiol concentrations despite numerous
oocyte maturations: a case report. BMC Pregnancy Childbirth. 2017 17:312. PMID: 28931393
草間特任助教(口頭発表)と白研究員(ポスター発表)が
SSR2017(ワシントンD.C.)にて、USDA-NIFA-AFRI Merit Awardを
ダブル受賞しました。